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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
ACTZ_HUMAN
USC-OGP 2-DE database
:
ACTZ_HUMAN
ACTZ_HUMAN
General information about the entry
View entry in simple text format
Entry name
ACTZ_HUMAN
Primary accession number
P61163
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Alpha-centractin; Short=Centractin; AltName: Full=ARP1; AltName: Full=Actin-RPV; AltName: Full=Centrosome-associated actin homolog;.
Gene name
Name=ACTR1A
Synonyms=CTRN1
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-7
{PLATELET 4-7}
Homo sapiens (Human)
map experimental info
PLATELET_4-7
MAP LOCATIONS:
SPOT OGP-0395
:
pI=5.99; Mw=45106
SPOT OGP-0396
:
pI=6.15; Mw=45106
SPOT OGP-0397
:
pI=6.18; Mw=45106
PLATELET_5-6
{PLATELET 5-6}
Homo sapiens (Human)
map experimental info
PLATELET_5-6
MAP LOCATIONS:
SPOT OGP-0700
:
pI=5.95; Mw=44642
SPOT OGP-0714
:
pI=5.96; Mw=41952
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1178
:
pI=6.52; Mw=44777
Cross-references
UniProtKB/Swiss-Prot
P61163; ACTZ_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
ACTZ_HUMAN
Primary accession number
P61163
Secondary accession number(s)
B2R6B0 P42024
Sequence was last modified on
May 10, 2004 (version 1)
Annotations were last modified on
March 15, 2017 (version 136)
Name and origin of the protein
Description
RecName: Full=Alpha-centractin; Short=Centractin; AltName: Full=ARP1; AltName: Full=Actin-RPV; AltName: Full=Centrosome-associated actin homolog;
Gene name
Name=ACTR1A
Synonyms=CTRN1
Encoded on
Name=ACTR1A; Synonyms=CTRN1
Keywords
Acetylation
;
ATP-binding
;
Complete proteome
;
Cytoplasm
;
Cytoskeleton
;
Direct protein sequencing
;
Nucleotide-binding
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X82206; CAA57690.1
; -; mRNA
EMBL
Z14978; CAA78701.1
; -; mRNA
EMBL
AK312506; BAG35407.1
; -; mRNA
EMBL
AL121928; CAC08404.1
; -; Genomic_DNA
EMBL
CH471066; EAW49685.1
; -; Genomic_DNA
EMBL
BC000693; AAH00693.1
; -; mRNA
EMBL
BC026016; AAH26016.1
; -; mRNA
CCDS
CCDS7536.1; -
; .
PIR
S29089; S29089
; .
RefSeq
NP_005727.1; NM_005736.3
; .
UniGene
Hs.153961; -
; .
ProteinModelPortal
P61163; -
; .
SMR
P61163; -
; .
BioGrid
115425; 73
; .
IntAct
P61163; 28
; .
MINT
MINT-5001146; -
; .
STRING
9606.ENSP00000358921; -
; .
iPTMnet
P61163; -
; .
PhosphoSitePlus
P61163; -
; .
SwissPalm
P61163; -
; .
BioMuta
ACTR1A; -
; .
DMDM
47117651; -
; .
OGP
P42024; -
; .
REPRODUCTION-2DPAGE
IPI00029468; -
; .
UCD-2DPAGE
P61163; -
; .
EPD
P61163; -
; .
MaxQB
P61163; -
; .
PaxDb
P61163; -
; .
PeptideAtlas
P61163; -
; .
PRIDE
P61163; -
; .
DNASU
10121; -
; .
Ensembl
ENST00000369905; ENSP00000358921
; ENSG00000138107; .
GeneID
10121; -
; .
KEGG
hsa:10121; -
; .
UCSC
uc001kvv.4; human
; .
CTD
10121; -
; .
DisGeNET
10121; -
; .
GeneCards
ACTR1A; -
; .
HGNC
HGNC:167; ACTR1A
; .
HPA
CAB037193; -
; .
HPA
HPA047443; -
; .
MIM
605143; gene
; .
neXtProt
NX_P61163; -
; .
OpenTargets
ENSG00000138107; -
; .
PharmGKB
PA24486; -
; .
eggNOG
KOG0676; Eukaryota
; .
eggNOG
COG5277; LUCA
; .
GeneTree
ENSGT00840000129754; -
; .
HOGENOM
HOG000233340; -
; .
HOVERGEN
HBG003771; -
; .
InParanoid
P61163; -
; .
KO
K16575; -
; .
OMA
RTIKEKC; -
; .
OrthoDB
EOG091G08LD; -
; .
PhylomeDB
P61163; -
; .
TreeFam
TF300420; -
; .
Reactome
R-HSA-2132295; MHC class II antigen presentation
; .
Reactome
R-HSA-2565942; Regulation of PLK1 Activity at G2/M Transition
; .
Reactome
R-HSA-380259; Loss of Nlp from mitotic centrosomes
; .
Reactome
R-HSA-380270; Recruitment of mitotic centrosome proteins and complexes
; .
Reactome
R-HSA-380284; Loss of proteins required for interphase microtubule organization from the centrosome
; .
Reactome
R-HSA-5620912; Anchoring of the basal body to the plasma membrane
; .
Reactome
R-HSA-8854518; AURKA Activation by TPX2
; .
SignaLink
P61163; -
; .
ChiTaRS
ACTR1A; human
; .
GeneWiki
ACTR1A; -
; .
GenomeRNAi
10121; -
; .
PRO
PR:P61163; -
; .
Proteomes
UP000005640; Chromosome 10
; .
Bgee
ENSG00000138107; -
; .
CleanEx
HS_ACTR1A; -
; .
ExpressionAtlas
P61163; baseline and differential
; .
Genevisible
P61163; HS
; .
GO
GO:0005814; C:centriole
; IEA:Ensembl; .
GO
GO:0005813; C:centrosome
; IDA:UniProtKB; .
GO
GO:0030137; C:COPI-coated vesicle
; IEA:Ensembl; .
GO
GO:0005737; C:cytoplasm
; IDA:LIFEdb; .
GO
GO:0005829; C:cytosol
; TAS:Reactome; .
GO
GO:0005869; C:dynactin complex
; TAS:ProtInc; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0002177; C:manchette
; IEA:Ensembl; .
GO
GO:0005875; C:microtubule associated complex
; TAS:ProtInc; .
GO
GO:0015630; C:microtubule cytoskeleton
; IDA:HPA; .
GO
GO:0043209; C:myelin sheath
; IEA:Ensembl; .
GO
GO:0005524; F:ATP binding
; IEA:UniProtKB-KW; .
GO
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II
; TAS:Reactome; .
GO
GO:0097711; P:ciliary basal body docking
; TAS:Reactome; .
GO
GO:0000086; P:G2/M transition of mitotic cell cycle
; TAS:Reactome; .
GO
GO:0007283; P:spermatogenesis
; IEA:Ensembl; .
GO
GO:0016192; P:vesicle-mediated transport
; TAS:ProtInc; .
InterPro
IPR004000; Actin
; .
InterPro
IPR020902; Actin/actin-like_CS
; .
InterPro
IPR004001; Actin_CS
; .
InterPro
IPR029909; Arp1
; .
PANTHER
PTHR11937; PTHR11937
; 1; .
PANTHER
PTHR11937:SF271; PTHR11937:SF271
; 1; .
Pfam
PF00022; Actin
; 1; .
PRINTS
PR00190; ACTIN
; .
SMART
SM00268; ACTIN
; 1; .
PROSITE
PS00432; ACTINS_2
; 1; .
PROSITE
PS01132; ACTINS_ACT_LIKE
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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